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The Parsemus Foundation’s mission is to create meaningful improvements in human and animal health and welfare by advancing innovative and neglected medical research. To make the most use of limited resources, the Parsemus Foundation works by funding key proof-of-concept studies and then publicizing them so that advances change treatment practice rather than disappearing into the scientific literature. Many of the studies supported by Parsemus involve low-cost approaches that are not under patent. The Foundation also leverages funding from larger foundations for the next stages of research and development of key projects.
The foundation has worked with researchers and scientists from across the world on research topics of interest. Grants usually support specific proof-of-concept studies and open-access publication. The foundation does not accept unsolicited grant applications, but is happy to hear from individuals working on projects of interest.
Publication of foundation-supported research is critical to ensuring that the results receive broad distribution, regardless of outcome. Scientific studies funded by the foundation must be published and freely available in an open-access-compliant journal, whether results are positive or negative. The foundation supports additional costs that may be incurred to ensure open access.
Parsemus Foundation’s maximum indirect cost reimbursement rate is 25% for organizations in low-income countries outside the United States, 20% for organizations in middle-income countries outside the United States, and 15% for organizations within the United States, Northern Europe, Canada, or Japan– with a cap of $20,000 per project. The foundation does not pay indirect costs on unrestricted awards and prizes (such as publication awards).
The Parsemus only supports research meeting high levels of animal care consistent with our work to improve animal welfare. Funded projects meet the European standards for animal care, which are much more stringent (and, we believe, humane) than the current US standards. Consistent with the advancements promoted by the (U.K.) Centre for the Replacement, Refinement, and Reduction of Animals in Research, a minimum number of animals is used, euthanasia at the end of the study is avoided if possible, and the study is a demonstrable step towards improving human and/or animal welfare. We have continued following these principles in all sponsored studies since then, including negotiating improved conditions for rabbits and providing farm-like housing for goats. Animals are adopted out at the conclusion of the study whenever possible.
Grantees seeking foundation support can make use of the following documents to explore whether they will be able to meet the conditions.
- European standards. All foundation-funded projects are required to meet or exceed these standards, or, in field-based rather than laboratory-based research, to improve the lives of the animals studied consistent with the spirit of these standards.
- National Centre for the Replacement, Refinement, and Reduction of Animals in Research. All foundation-funded projects are required to take the NC3Rs recommendations into account.
- NC3Rs leaflet with overview of NC3Rs projects and services.
- Animal Welfare Institute: Making Lives Easier for Animals.
- NC3Rs Primate Guidelines.
- Reinhardt: Taking Better Care of Monkeys and Apes
- Refinements in husbandry, care and common procedures for non-human primates: Ninth report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement.
- Refining rabbit care: A resource for those working with rabbits in research (RSPCA and UFAW, 2008).
- Supplementary resources regarding rabbit care and housing:
National Centre for the Replacement, Refinement, and Reduction of Animals in Research – rabbit page.
- Animal Welfare Institute Comfortable Quarters for Dogs in Research Institutions.
- RSPCA Dogs: Good Practice for Housing and Care (2011).
- Enrichment safety tips: Learning from others’ experience