Breast Cancer Prevention

An intraductal approach is gaining ground as a way to evaluate and clear out precancerous changes in the breast ducts Parsemus Foundation encourages research on simple approaches that could have a big impact, including the intraductal approach to early breast cancer– preventing, or eliminating, early cellular changes in the milk ducts (where the great majority… Read more

Other female sterilization approaches

Ultrasound-guided female sterilization Summary Ultrasound can be used to guide an injection into the uterus, uterine horns, fallopian tubes, or ovaries of female mammals, including dogs and humans. We have discovered that it is quite hard to inject into the ovaries due to the difficulty of puncturing the hard outer capsule. Ultrasound can be used… Read more

Street dog identification/marking

Marking Street Dogs Promoting evidence-based best practices Parsemus Foundation is helping support research on ways to sterilize dogs and cats without surgery and anesthesia. But the current methods of marking which animals have been sterilized all require anesthesia. This creates a Catch-22! In dogs, ear-notching (cutting a chunk out of the ear and then sealing… Read more

Shrinking tumors nonsurgically

Tumor bulk reduction Older dogs often get mammary tumors and benign masses. Though benign, these lumps can cause problems if they get very large or start to restrict movement. But owners are often reluctant to put their older dogs under anesthesia for surgery, or they do not have the money. Calcium chloride in alcohol, which… Read more

Modernizing spay practice for females

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Ovary-Sparing Spay

Promoting choice for optimal animal health Ovary-sparing spay may be a way to have one’s cake and eat it too: a way to spay female dogs (thus addressing population concerns), without the negative health impacts from hormone loss. Ovary-sparing spay is approved by the AVMA. Find veterinarians in your area offering ovary-sparing spay as an… Read more

Other contraceptive research

Men need more contraception options Did you know that there are over 85 million unintended pregnancies worldwide each year? With only condoms and vasectomy as contraceptive options, men currently have limited choices to control their reproduction. Demand for a non-hormonal, highly effective contraceptive for men is increasing, with use expected to reduce the incidence of… Read more


Ultrasound effectiveness varies by species Ultrasound has been proposed as a noninvasive contraceptive, but the effect varies greatly depending on the species and the methods applied. While ultrasound was an effective contraceptive in rats and a permanent sterilant in dogs, study results in monkeys and self-reported outcomes in humans were disappointing. In 2007, Parsemus Foundation sponsored… Read more


Vasalgel, a multi-year contraceptive VasalgelTM is being developed as a long-acting, non-hormonal contraceptive with a significant advantage over vasectomy: it is likely to be more reversible. The procedure is similar to a no-scalpel vasectomy, except a gel is injected into the vas deferens (the tube the sperm swim through), rather than cutting the vas (as… Read more