A long-acting, nonhormonal contraceptive for men, with thousands of men on the waitlist.


Parsemus Foundation is supporting research that focuses on simple, inexpensive therapies.

Dogs & Cats

Calcium chloride (“Calchlorin”), a low-cost, nonsurgical neuter shot available to vets now.


Veterinarians open to offering ovary-sparing spay, vasectomy and other alternatives to traditional spay/neuter

iStock_4516712_MegaPhone_BlueOur Mission

The Parsemus Foundation works to create meaningful improvements in human and animal health and welfare by advancing innovative and neglected medical research. The foundation’s focus is on supporting small proof-of-concept studies and then pursuing press coverage of the results, so that the advances change treatment practice rather than disappearing into the scientific literature. Many of the studies we support involve low-cost approaches that are not under patent. When supporting development of technologies under patent, the Parsemus Foundation coordinates with larger funders to make sure support is contingent upon strong public-sector pricing agreements.

Current areas of focus are contraceptive development (particularly long-acting nonhormonal male methods); nonhormonal, nonsurgical sterilization for animals; and noninvasive treatment for benign prostatic hyperplasia. And that’s not all — additional projects are listed in the page links above. Applications for support are by invitation only except where specifically noted. Please see Our History page for selected highlights and milestones.

Recent News

Featured Studies

Health consequences of canine spay/neuter and alternative approaches

Innovative Veterinary Care Journal publishes a review of research on the consequences of canine gonadectomy and of methods to sterilize dogs while preserving hormones for long-term health. In the United States, spaying or neutering a dog has become standard practice to reduce pet overpopulation. Yet recent research has shed light on the long-term health impacts… Read more

Calcium chloride chemical sterilant in testicle vs. epididymis

Calcium chloride (CaCl) has been used as a nonsurgical alternative to castrating male dogs and cats. Dr. Raffaella Leoci of the University of Bari in Italy is the lead author of the studies elucidating the optimal formulation for using CaCl in alcohol to sterilize dogs through testicular injection. Her research team has conducted a controlled… Read more