The Parsemus Foundation works to create meaningful improvements in human and animal health and welfare by advancing innovative and neglected medical research. The foundation’s focus is on supporting small proof-of-concept studies and then pursuing press coverage of the results, so that the advances change treatment practice rather than disappearing into the scientific literature. Many of the studies we support involve low-cost approaches that are not under patent. When supporting development of technologies under patent, the Parsemus Foundation coordinates with larger funders to make sure support is contingent upon strong public-sector pricing agreements.
Current areas of focus are contraceptive development (particularly long-acting nonhormonal male methods); nonhormonal, nonsurgical sterilization for animals; and noninvasive treatment for benign prostatic hyperplasia. And that’s not all — additional projects are listed in the page links above. Applications for support are by invitation only except where specifically noted. Please see Our History page for selected highlights and milestones.
We always need to focus on the males just as much as females. Feline AIDS, cat fight abscesses, and human bites usually occur from intact males. Roaming from being intact increases the risk of hit by cars.
Dr. Cole Bierbaum, veterinarian, Feline Rescue and Return (FuRR), Little Rock, AR
I currently have over 300 cats waiting for spay/neuter. We handle 26 rural counties in middle GA… I would offer $5-10 “Fix ’em Fridays” But would prefer the product that REDUCES the testosterone levels. However beggars can not be choosers and therefore we will happily accept ANYTHING that reduces our unwanted pet population numbers. Remember we have no shelters, no animal controls—shooting is the greatest form of euthanasia in the country areas by people/owners who just can’t deal with all them critters anymore.
Barbara Bruigom, President/Founder, The Rescue Ranch, McRae, Georgia
Adopters want to know male cats won’t spray and male dogs won’t have the fighting, roaming, humping tendencies. If male chemical sterilization was available that was permanent and reduced testosterone thus reducing undesirable behaviors, we could alter more females with the surgical time saved and hope that soon a chemical sterilant will become available for females. In our application the new product would be game changing. A simple injection that did both [sterilizes and modifies behavior] would be a good answer and well worth the dollars spent for regulatory approval. An even better answer would be a chemical sterilant for males and females but reducing our surgical time by 50% for the male population would be huge.
Linda F., LVT, Clinic Manager, WAIF Animal Shelter, Whidbey Island, WA
Animal Control, whether or not it performs spays or neuters of pets, is greatly impacted by the animals that are not altered. This impact is felt in two ways. First, most animals are abandoned at shelters due to behavioral problems and many of these problems are associated with intact males and testosterone-related. Secondly, the unintended breeding of unaltered pets adds significantly to the population of pets and increases the cost of any animal control program.
Mitch S., Washoe County Regional Animal Services, Reno, NV
Having a chemical solution to replace [female] spayings would be a total revolution and have a bigger impact; but still, an injectable sterilant for males would be of much help and reduce our costs significantly. We do an average of 2,000 spay/neuterings per year, 35% males. Considering that last year we spent 60,000 euros on anesthetics and medicines (mostly antibiotics), we could save approximately 10,000 euros [approx. $13,000] per year and increase the number of castrations thanks to a quicker procedure.
President, dog rescue and TNR organization, Romania
I think it would be game changing in feral cats. To be able to do this in the field would be amazing.
Founder, rescue group, South-central United States
I think it would be game changing if it got FDA approval. I will not use [a product that doesn’t change behavior] because behavior and population weigh equally to me. People are not as interested in animals with behavior issues, and if they don’t get adopted then we still have a shelter population problem.
Consulting veterinarian, cat rescue organization, Wisconsin
I think for cost reasons alone it would appeal to some of our residents who are hesitant to bring the cats in because of cost factor but would be more willing to do so on cats no one owns if a less expensive option were available. I do believe that in our area we have an equal number of people who bring animals to our S/N clinic for nuisance reasons. The cat fights, yowling/howling, destruction of property from marking, escaping dogs (and cats), which most attribute to the males… So I do not think it is only a female problem. We see a lot of male aggression that is more manageable after neuter and can often be eliminated if done before puberty.
Lisa D., DVM, MBA, Chief Staff Veterinarian, Yavapai Humane Society, Prescott, Arizona
I know that I for one would NOT have a male cat who would still spray…and the leg-lifting and humping of formerly chained dogs has to be stopped for our rescue to be effective. So I’m for the choice of spending the time and money to use the sterilant that changes behavior.
Tamira T., Founder, Dogs Deserve Better, Tipton, PA
So many don’t want to put their animal through surgery. This would solve that argument. It would be great to use the injection when surgery is not a option.
Karen R., President/CEO, Central Arkansas SPCA, Arkansas, USA
Having control over when I have children is the foremost thing in my life. I place great value on having freedom of choice and freedom from worry. Also, being a person with not much money living in a third world country, a cheap contraceptive is imperative…
Anonymous, South Africa
As a male I would not take any contraceptive that altered my hormonal balance. And the idea of getting a MONTHLY injection – are you crazy??? (This is probably why surveys come back saying there’s limited interest in male contraceptives – given that sort of choice, I’m not interested either!). However, a one-time injection (every 5-10 years) such as RISUG/Vasalgel that does not mess with the hormonal balance, and is reversible… what’s not to like? Sign me up, NOW please!
Terry S., Australia
I do not wish to further my genetic line due to a severe bleeders disease, which also makes normal vasectomy a no-go…
I would like the opportunity to be more intimate with my partner and condoms bar that, beyond the conventional ‘doesn’t feel as good’ argument. However, I am extremely concerned about the failure rates of the Pill due to human error and would like to take some responsibility for my future finances into my own hands without being abstinent.
New college graduate, age 22, Florida, USA
I want control of my fertility that is safe, convenient to use and totally effective. That way I can be in control of my life rather than putting it in the hands of women and government agencies.
S. Gee, South Korea
I am a woman and as a migraine sufferer, my contraceptive choices are limited to IUDs or progestin-only pills. Since I experience unwanted side effects with these, we rely on condoms. A longer-term “no-worry” solution would be much preferred. It would be worth the cost as opposed to an unwanted pregnancy!
Sara D., married, no kids, Ohio, USA
Innovative Veterinary Care Journal publishes a review of research on the consequences of canine gonadectomy and of methods to sterilize dogs while preserving hormones for long-term health. In the United States, spaying or neutering a dog has become standard practice to reduce pet overpopulation. Yet recent research has shed light on the long-term health impacts… Read more
Calcium chloride (CaCl) has been used as a nonsurgical alternative to castrating male dogs and cats. Dr. Raffaella Leoci of the University of Bari in Italy is the lead author of the studies elucidating the optimal formulation for using CaCl in alcohol to sterilize dogs through testicular injection. Her research team has conducted a controlled… Read more