Better breast cancer approaches

Understanding stress and breast cancer metastasis

Researchers from the University of Basel have helped to unravel the relationship between stress hormones and cancer metastasis. Using a rodent model of triple negative breast cancer, the scientists found that metastases had increased levels of glucocorticoid receptor (GR). Mice with metastases also had higher levels of stress hormones like cortisol, which increased GR levels…. Read more


Hope for metastatic triple-negative breast cancer

Breast cancer is a very active area of research, and we regularly review publications about new treatments. But experience shows that early-stage, preclinical research results do not often translate into successful treatment in humans. So when we saw the promising outcomes of a clinical trial of a new “smart drug” to treat women with metastatic… Read more


How diet can influence breast cancer

Diet and exercise play a role in the development of a number of chronic diseases, such as Alzheimer’s, diabetes and heart disease. Cancer and diet have also been associated, but until now, scientists did not understand why. Researchers at the Medical University of South Carolina have found the likely link. AGEs – or advanced glycation… Read more


Vitamin D and cancer

High levels of vitamin D have been related to lower levels of breast cancer, report scientists from the University of California San Diego. Expanding on epidemiological studies relating higher cancer levels in individuals with vitamin D deficiency,  the current study published in PLOS One utilized data from two randomized  and one prospective clinical trials. Postmenopausal women… Read more


Chemotherapy not necessary for most early-stage breast cancer patients

Results of the TAILORx clinical study may change the treatment recommendations for women with early-stage breast cancer. A recent report indicated that for most women with an intermediate risk score resulting from the 21-gene expression test, there was no benefit of taking chemotherapy in addition to hormone therapy. Authors of the study, which is to be… Read more


Flu vaccine and erectile dysfunction drugs to treat cancer?

Researchers from Ottawa have found that a combination of a flu vaccine and erectile dysfunction drug was able to reduce the number of cancer metastases following tumor removal surgery in a mouse model. While surgery is an effective first step in removing cancerous tumors, the surgery can suppress the immune system – giving an advantage… Read more


Electronic nose sniffs out breast cancer

Scientists have recently developed methods to detect breast cancer by measuring a patient’s breath and urine. They used electronic nose gas sensors for breath, along with gas-chromatography mass spectrometry to quantify substances found in urine. These diagnostic methods are inexpensive and were found to have 95% accuracy. The new method may be particularly useful in… Read more


Simple treatment for chemotherapy pain

Individuals undergoing chemotherapy often suffer from side effects, including pain or numbness in the hands and feet (called chemotherapy-induced peripheral neuropathy). Sometimes it is so severe that they delay or avoid chemotherapy treatment. A recently published prospective study highlighted the significant benefits of a simple solution: keeping the hands and feet cold during chemotherapy treatment…. Read more


Underutilized nonsurgical treatment for uterine fibroids

Most women have heard about uterine fibroids – benign tumors that affect 70-80% of women at some point in their lives. However, very few women are aware that they can be removed without surgery. The procedure is called uterine fibroid embolization (UFE). A recent survey conducted by the Society of Interventional Radiology reported that 44% of… Read more