Research Papers

Review of health implications of dog spay/neuter

Spaying and neutering can lead to long-term health problems in dogs. A recent review article summarizes these problems and illuminates the role of luteinizing hormone (LH). Ovaries and testes — the gonads — produce hormones such as estrogen and testosterone. Research has shown that removal of the gonads through spaying and neutering is associated with… Read more


Electromagnetic therapy effective for enlarged prostate

An inexpensive electromagnetic therapy quickly improved outcomes for men with enlarged prostates, according to a new study by researchers at Sapienza University of Rome with funding from the Parsemus Foundation. The results were published recently in Andrology, the highest ranked journal in andrological research. Benign prostatic hyperplasia (BPH), enlargement of the prostate, is a common… Read more


Spayed female dogs at higher risk of brain tumors

In a novel study using canine brain scans, scientists have reported that spayed females had an increased relative risk of brain tumors — 11 times that of intact females. The authors cited the importance of estrogen to brain health, and related their work in dogs to findings in women regarding higher incidence of dementia than… Read more


Connection between postmenopausal breast cancer and heart disease

Current treatments for breast cancer result in an increased risk of cardiovascular disease, as reported in the journal Menopause. A group of postmenopausal women who survived breast cancer were compared to a matched group without breast cancer. The Brazilian research team found that previous breast cancer was associated with metabolic syndrome, diabetes, atherosclerosis, high triglycerides, and… Read more


Developments in Alzheimer’s research

Given the rapid aging of the world population, it’s no surprise that research on Alzheimer’s disease has become a scientific focus. Simply understanding the mechanisms resulting in the disease has been a major undertaking, but we’re starting to make progress. A research study recently published in Nature Communications by scientists at the Van Andel Research… Read more


Understanding stress and breast cancer metastasis

Researchers from the University of Basel have helped to unravel the relationship between stress hormones and cancer metastasis. Using a rodent model of triple negative breast cancer, the scientists found that metastases had increased levels of glucocorticoid receptor (GR). Mice with metastases also had higher levels of stress hormones like cortisol, which increased GR levels…. Read more


Hope for metastatic triple-negative breast cancer

Breast cancer is a very active area of research, and we regularly review publications about new treatments. But experience shows that early-stage, preclinical research results do not often translate into successful treatment in humans. So when we saw the promising outcomes of a clinical trial of a new “smart drug” to treat women with metastatic… Read more


How diet can influence breast cancer

Diet and exercise play a role in the development of a number of chronic diseases, such as Alzheimer’s, diabetes and heart disease. Cancer and diet have also been associated, but until now, scientists did not understand why. Researchers at the Medical University of South Carolina have found the likely link. AGEs – or advanced glycation… Read more


Spinal fusion procedures may not help

For those suffering from pain related to spinal fractures due to osteoporosis, spinal fusion may not be the answer. Cementing crumbling vertebrae to fuse bones together – called vertebroplasty – is common practice for osteoporosis patients. Over 750,000 vertebroplasty procedures are conducted annually in the United States. According to a task force of the American… Read more


“Slow medicine” advocates warn about overused medical tests

We’ve all seen advertising for genetic testing services, offering insight into your ancestry as well as health based on your genetic code. But Drs. Michael Hochman and Pieter Cohen warn that genetic tests offered directly to consumers without input from a physician or geneticist can be problematic. They note that genetic tests for BRCA mutations… Read more