Current treatments for breast cancer result in an increased risk of cardiovascular disease, as reported in the journal Menopause. A group of postmenopausal women who survived breast cancer were compared to a matched group without breast cancer. The Brazilian research team found that previous breast cancer was associated with metabolic syndrome, diabetes, atherosclerosis, high triglycerides, and… Read more
Given the rapid aging of the world population, it’s no surprise that research on Alzheimer’s disease has become a scientific focus. Simply understanding the mechanisms resulting in the disease has been a major undertaking, but we’re starting to make progress. A research study recently published in Nature Communications by scientists at the Van Andel Research… Read more
We’ve all seen it – pet parents who waltz into dog parks and let their canines run amok without any consideration. Here’s how hormones and training play a role in this social environment, and what you can do to keep your pup safe. The dog park can be an idyllic setting for you and your… Read more
The “Rat Scratcher” was presented with the 2019 Janet Wood Innovation Award at the Institute of Animal Technology Congress in Liverpool, England earlier this month. The award, a program of the Datesand Group, aims to encourage laboratory animal technicians to come up with ideas that support the Three R’s of animal research: replacement, reduction and… Read more
Researchers from the University of Basel have helped to unravel the relationship between stress hormones and cancer metastasis. Using a rodent model of triple negative breast cancer, the scientists found that metastases had increased levels of glucocorticoid receptor (GR). Mice with metastases also had higher levels of stress hormones like cortisol, which increased GR levels…. Read more
Breast cancer is a very active area of research, and we regularly review publications about new treatments. But experience shows that early-stage, preclinical research results do not often translate into successful treatment in humans. So when we saw the promising outcomes of a clinical trial of a new “smart drug” to treat women with metastatic… Read more
Diet and exercise play a role in the development of a number of chronic diseases, such as Alzheimer’s, diabetes and heart disease. Cancer and diet have also been associated, but until now, scientists did not understand why. Researchers at the Medical University of South Carolina have found the likely link. AGEs – or advanced glycation… Read more
The Parsemus Foundation began working on a new male contraceptive called Vasalgel a number of years ago. In 2013, Revolution Contraceptives was formed as a social venture company to develop Vasalgel and bring it to market. Revolution Contraceptives has grown over the last couple of years to meet the increasingly diverse and complex demands related… Read more
Revolution Contraceptives received a $200,000 grant from the Male Contraceptive Initiative (MCI) to advance Vasalgel towards human trials. The grant will support preclinical studies that will evaluate contraceptive effectiveness, procedural simplicity, reversibility, and safety. This proof-of-concept study will build on results from earlier preclinical studies and should support a future application for clinical trials in… Read more
For those suffering from pain related to spinal fractures due to osteoporosis, spinal fusion may not be the answer. Cementing crumbling vertebrae to fuse bones together – called vertebroplasty – is common practice for osteoporosis patients. Over 750,000 vertebroplasty procedures are conducted annually in the United States. According to a task force of the American… Read more