Research Papers

“Slow medicine” advocates warn about overused medical tests

We’ve all seen advertising for genetic testing services, offering insight into your ancestry as well as health based on your genetic code. But Drs. Michael Hochman and Pieter Cohen warn that genetic tests offered directly to consumers without input from a physician or geneticist can be problematic. They note that genetic tests for BRCA mutations… Read more


Health consequences of canine spay/neuter and alternative approaches

Innovative Veterinary Care Journal publishes a review of research on the consequences of canine gonadectomy and of methods to sterilize dogs while preserving hormones for long-term health. In the United States, spaying or neutering a dog has become standard practice to reduce pet overpopulation. Yet recent research has shed light on the long-term health impacts… Read more


“You are what you eat” may apply to breast tissue health

You’ve probably heard of the “microbiome” in your gut, but did you know that the glands in breast tissue have a microbiome as well? Even more amazing, the breast microbiome can be influenced by what you eat. Scientists at Wake Forest Medical School recently published their findings in Cell Reports on a study conducted in… Read more


Study contradicts assumptions about hormones and aggressiveness in dogs

We’ve all heard that spaying or neutering your dog (gonadectomy, or removal of the gonads, i.e. the ovaries or testes) will help reduce its aggressiveness. However, a recent study including over 13,000 dogs concluded that this assumption is incorrect. In the U.S., veterinarians and animal welfare organizations have long supported gonadectomy as a way to… Read more


Vitamin D and cancer

High levels of vitamin D have been related to lower levels of breast cancer, report scientists from the University of California San Diego. Expanding on epidemiological studies relating higher cancer levels in individuals with vitamin D deficiency,  the current study published in PLOS One utilized data from two randomized  and one prospective clinical trials. Postmenopausal women… Read more


Chemotherapy not necessary for most early-stage breast cancer patients

Results of the TAILORx clinical study may change the treatment recommendations for women with early-stage breast cancer. A recent report indicated that for most women with an intermediate risk score resulting from the 21-gene expression test, there was no benefit of taking chemotherapy in addition to hormone therapy. Authors of the study, which is to be… Read more


Flu vaccine and erectile dysfunction drugs to treat cancer?

Researchers from Ottawa have found that a combination of a flu vaccine and erectile dysfunction drug was able to reduce the number of cancer metastases following tumor removal surgery in a mouse model. While surgery is an effective first step in removing cancerous tumors, the surgery can suppress the immune system – giving an advantage… Read more


Electronic nose sniffs out breast cancer

Scientists have recently developed methods to detect breast cancer by measuring a patient’s breath and urine. They used electronic nose gas sensors for breath, along with gas-chromatography mass spectrometry to quantify substances found in urine. These diagnostic methods are inexpensive and were found to have 95% accuracy. The new method may be particularly useful in… Read more


Elderly patients missing out on minimally invasive procedures

Minimally invasive surgery (MIS) has proven benefits over “open surgery”: fewer complications, shorter hospitalization, lower rates of readmission and mortality, and lower health care costs. Unfortunately, the population that might benefit the most from this approach is under-served. A recently published study used a Medicare database to analyze minimally invasive vs. traditional open surgeries in elderly… Read more


Improved health with new treatment regimen for adrenal insufficiency

If you or someone you know has adrenal insufficiency, you probably understand how difficult it is to regulate glucocorticoid replacement therapy. That’s because the body normally has various levels of cortisol throughout the day as well as in response to stressors. Glucocorticoid over-treatment may result in weight gain and metabolic impairment, with dose reduction the… Read more